Polina G, Grimson WEL, Shenton ME, Kikinis R (2001) Deformation analysis for shaped based classification, information processing in medical imaging. In: Ninth international conference on medical image understanding and analysis, Bristol, 19–20 July 2005, p 167–170 Olmos S, Bossa M, Styner M (2005) PCA-based filtering for hypothesis testing on hippocampus shape differences between schizophrenics and normals. Jonke E, Schaefer K, Freudenthaler JW, Prossinger H, Bookstein FL (2003) A cephalometric comparison of skulls from different time periods–the Bronze Age, the 19th century and the present. J Craniofac Surg 18:219–224Įrcan I, Ocakoglu G, Guney I, Yazici B (2008) Adaptation of generalizability theory for inter-rater reliability for landmark localization. Įrcan I, Etoz A, Guney I, Ocakoglu G, Turan Ozdemir S, Kan I, Kahveci R (2007) Statistical shape analysis of nose in Turkish young adults. Houghton-Mifflin/Lahaska Press, Bostonĭryden I (2004) Shapes: statistical shape analysis. In: Erford BT (ed) Assessment for counselors. Forensic Sci Int 159:126–146ĭeQuardo JR, Keshavan MS, Bookstein FL, Bagwell WW, Green WDK, Sweeney JA, Haas GL, Tandon R, Schooler NR, Pettegrew JW (1999) Landmark-based morphometric analysis of first-episode schizophrenia. Proc Natl Acad Sci 95:11406–11411ĭe Greef S, Claes P, Vandermeulen D, Mollemans W, Suetens P, Willems G (2006) Large-scale in vivo Caucasian facial soft tissue thickness database for craniofacial reconstruction. Epilepsia 32:778–782Ĭsernansky JG, Joshi S, Wang L, Haller JW, Gado M, Miller JP, Grenander U, Miller MI (1998) Hippocampal morphometry in schizophrenia by high dimensional brain mapping. Teratology 64:4–32Ĭavalheiro EA, Leite JP, Bortolotto ZA, Turski WA, Ikonomidou C, Turski L (1991) Long-term effect of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. Cambridge University Press, New Yorkīookstein FL, Sampson PD, Streissguth AP, Connor PD (2001) Geometric morphometrics of corpus callosum and subcortical structures in the fetal-alcohol-affected brain. IEEE Trans Pattern Anal Machine Intell 11:567–585īookstein FL (1991) Morphometrics tools for landmark data. Hippocampus 11:452–468īookstein FL (1989) Principal warps: thin-plate splines and the decomposition of deformations. J Anat 206:373–385Īndre V, Marescaux C, Nehlig A, Fritschy JM (2001) Alterations of hippocampal gabaergic system contribute to development of spontaneous recurrent seizures in the rat lithium pilocarpine model of temporal lobe epilepsy. Anat Rec 285:690–698Īldridge K, Kane AA, Marsh JL, Yan P, Govier D, Richtsmeier JT (2005b) Relationship of brain and skull in pre- and postoperative sagittal synostosis. J Anat 201:31–39Īldridge K, Kane AA, Marsh JL, Panchal J, Boyadjiev SA, Yan P, Govier D, Ahmad W, Richtsmeier JT (2005a) Brain morphology in nonsyndromic unicoronal craniosynostosis. Sage, LondonĪldridge K, Marsh JL, Govier D, Richtsmeier JT (2002) Central nervous system phenotypes in craniosynostosis. This study may serve as an initial reference for future studies on shape alteration of the hippocampus associated with certain medical conditions.Īldenderfer MS, Blashfield RK (1989) Cluster analysis. In conclusion, our landmark-based methodology detected regional differences in the hippocampus in epilepsy. The results strongly indicated that the normalized hippocampal shape of the epileptic group was different from the nonepileptic group deformation was seen most significantly in the medial regions of the cornu ammonis (CA1 and CA3) of the hippocampus. Nineteen rat brains (ten healthy and nine epileptic) with hematoxylin and eosin images of the hippocampus were used. Statistical shape analysis is of increasing interest to the neuroimaging community because of its potential for locating morphological changes. We have used the statistical shape analysis method to illustrate hippocampal shape deformation due to epilepsy. In this study, we aimed to (1) propose landmarks for the hippocampus in a rat brain using an experimental study and (2) investigate hippocampus shape changes in a rat brain with epilepsy using the statistical shape analysis method.
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